Prediagnostic Circulating Anti-Müllerian Hormone Concentrations Are Not Associated with Prostate Cancer Risk
نویسندگان
چکیده
منابع مشابه
Short Communication Prediagnostic Circulating Anti-M€ ullerian Hormone Concentrations Are Not Associated with Prostate Cancer Risk
Despite considerable research, the pathogenesis of prostate cancer remains poorly understood. Meanwhile, PSA testing has shifted prostate cancer case populations for study to include a greater proportion of asymptomatic and indolent disease. Thus, efforts to identify prostate cancer biomarkers—particularly for aggressive disease—are required to elucidate pathogenesis and aid screening efficacy....
متن کاملAnti-Müllerian Hormone Is Not Associated with Cardiometabolic Risk Factors in Adolescent Females
OBJECTIVES Epidemiological evidence for associations of Anti-Müllerian hormone (AMH) with cardiometabolic risk factors is lacking. Existing evidence comes from small studies in select adult populations, and findings are conflicting. We aimed to assess whether AMH is associated with cardiometabolic risk factors in a general population of adolescent females. METHODS AMH, fasting insulin, glucos...
متن کاملAnti-Müllerian hormone concentrations in premenopausal women and breast cancer risk.
Laboratory models support an inverse association between anti-Müllerian hormone (AMH) and breast tumor development. Human studies are lacking; one study (N = 105 cases, 204 controls) with prospectively collected serum reported the opposite-an approximate 10-fold increase in breast cancer risk comparing fourth with first quartile AMH levels. We investigated the relation between serum AMH levels ...
متن کاملAnti-Müllerian hormone concentrations in maternal serum during pregnancy.
BACKGROUND In females, anti-Müllerian hormone (AMH) is expressed only by the ovary. AMH is secreted by the granulosa cells of ovarian follicles and appears to regulate early follicle development. AMH is detected in serum from women of reproductive age and its levels vary slightly with the menstrual cycle, reaching the peak value in the late follicular phase. This study investigated serum AMH le...
متن کاملAnti-Müllerian hormone and anti-Müllerian hormone type II receptor polymorphisms are associated with follicular phase estradiol levels in normo-ovulatory women.
BACKGROUND In mice, anti-Müllerian hormone (AMH) inhibits primordial follicle recruitment and decreases FSH sensitivity. Little is known about the role of AMH in human ovarian physiology. We hypothesize that in women AMH has a similar role in ovarian function as in mice and investigated this using a genetic approach. METHODS The association of the AMH Ile(49)Ser and the AMH type II receptor (...
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ژورنال
عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention
سال: 2014
ISSN: 1055-9965,1538-7755
DOI: 10.1158/1055-9965.epi-14-0803